Myxofibrosarcoma of the sinus piriformis: case report and literature review

Myxofibrosarcoma is a common sarcoma in the extremities of older people, but is rare in thehead and neck region. Here, we report the case of a 42-year-old male patient in whommyxofibrosarcoma generated from the sinus piriformis. Histopathologically, the tumor wascharacterized by spindle cellular proliferation with moderate cellular density in fibromyxoidstroma. Immunohistochemically, the tumor cells showed positive reactivity for vimentin, Ki-67, smooth muscle actin, and CD34, but negative staining for S-100. Based on these results,the tumor was diagnosed as a low-grade myxofibrosarcoma. Resection of the tumor wasperformed via a transcervical approach. The patient's postoperative clinical course wasuneventful and no local recurrence or distant metastasis has been found so far. The pathology,clinical characteristics, and treatment of myxofibrosarcoma are also reviewed.

via World Journal of Surgical Oncology